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Home / Drug Test Cutoff Levels: SAMHSA Federal Screening and Confirmation Limits

Drug Test Cutoff Levels: SAMHSA Federal Screening and Confirmation Limits

Updated · By the DrugTestAnswers editorial team

SAMHSA drug test cutoff levels - laboratory testing equipment

A drug test isn't really a yes/no question. It asks "is there more than X nanograms per milliliter?" That X is the cutoff, and it's the most important number nobody tells you about.

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Ad: we may earn a commission if you buy through this link. Information only, not medical or legal advice. Tampering with a drug test can be illegal and usually counts as a refusal. The only sure way to pass is to not use.

Urine test strip - SAMHSA drug test cutoff levels
Urine test strip. Photo: Wikimedia Commons, see image credits.

Urine cutoffs (HHS Mandatory Guidelines, 2017)

Drug classInitial screen (ng/mL)Confirmatory test (ng/mL)
Marijuana metabolite (THC-COOH)5015
Cocaine metabolite (benzoylecgonine)150100
Codeine / morphine2,0002,000
Hydrocodone / hydromorphone300100
Oxycodone / oxymorphone100100
6-acetylmorphine (heroin)1010
Amphetamine / methamphetamine500250
MDMA / MDA500250
PCP2525
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Ad: we may earn a commission if you buy through this link. Information only, not medical or legal advice. Tampering with a drug test can be illegal and usually counts as a refusal. The only sure way to pass is to not use.

Oral fluid cutoffs (HHS Mandatory Guidelines, 2019)

Drug classInitial (ng/mL)Confirmatory (ng/mL)
THC42
Cocaine / benzoylecgonine158
Codeine / morphine3015
6-AM42
Amphetamine / methamphetamine5025
MDMA5025
PCP32
Oxycodone / oxymorphone3015

Sources: SAMHSA, HHS Mandatory Guidelines for Federal Workplace Drug Testing Programs (Federal Register 2017, urine; 2019, oral fluid). Private employers often copy these numbers, but some labs and home kits use different cutoffs, such as 20 ng/mL for THC.

What this means for you

A lower cutoff catches smaller amounts for longer. A home strip is only useful if you know its cutoff, so check the box. A positive screen is not the final word: in regulated programs it must be confirmed by GC-MS or LC-MS and reviewed by a Medical Review Officer, who'll ask about prescriptions.

See the 10-panel home drug test at TestClear →

Ad: we may earn a commission if you buy through this link. Information only, not medical or legal advice. Tampering with a drug test can be illegal and usually counts as a refusal. The only sure way to pass is to not use.

Straight talk, brother to brother.

No product can promise you a pass, and the only certain way is to not use. Tampering with a drug test can be illegal and is usually treated as a refusal. We never help anyone beat DOT, federal, safety-sensitive, or court-ordered tests. If substance use is getting on top of you, call the free, confidential SAMHSA National Helpline on 1-800-662-4357 (24/7, English and Spanish), or call or text 988 in a crisis. Source: samhsa.gov.